| 发明名称 |
EPIGENETIC CO-REPRESSORS OF THE GAMMA-GLOBIN GENE AND METHODS OF USING SAME |
| 摘要 |
<p>This disclosure describes methods of screening for compounds that disrupt the interaction between DNMT1 and the gamma-globin promoter or between LSD-1 and the gamma-globin promoter. This disclosure describes methods of screening for compounds that de-repress the gamma-globin gene.</p> |
| 申请公布号 |
EP2714921(A2) |
申请公布日期 |
2014.04.09 |
| 申请号 |
EP20120789967 |
申请日期 |
2012.05.24 |
| 申请人 |
REGENTS OF THE UNIVERSITY OF MICHIGAN |
发明人 |
ENGEL, JAMES DOUGLAS;TANABE, OSAMU;SHI, LIHONG |
| 分类号 |
C12Q1/02;A61K31/00;C12N15/52;C12N15/63;C12Q1/26;C12Q1/48;G01N33/68 |
主分类号 |
C12Q1/02 |
| 代理机构 |
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