发明名称 CRYSTALLINE FORMS OF 3-[5-CHLORO-4-[(2,4-DIFLUOROBENZYL) OXY]-6-OXOPYRIMIDIN-1(6H)-YL]-N-(2-HYDROXYETHYL)-4-METHYLBENZAMIDE
摘要 Crystalline forms of the p38 kinase inhibitor 3-[5-chloro-4-[(2,4-difluorobenzyl)oxy]-6-oxopyrimidin-1(6H)-yl]-N-(2-hydroxyethyl)-4-methylbenzamide is provided. Also provided are combinations and pharmaceutical compositions comprising the crystalline forms, and methods for the prophylaxis and/or treatment of a p38 kinase-mediated condition comprising administering to a subject a therapeutically effective amount of the crystalline forms.
申请公布号 EP1802589(B1) 申请公布日期 2014.04.09
申请号 EP20050787468 申请日期 2005.10.03
申请人 PHARMACIA & UPJOHN COMPANY LLC 发明人 SELBO, JON, G.
分类号 C07D239/52;A61K31/513 主分类号 C07D239/52
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