发明名称 METHOD OF PREPARING 1,3-DIOXOLANE-2-ONE AND CARBOXYLATE ESTER BY ACYL TRANSLOCATION UNDER BASIC TREATMENT CONDITION
摘要 PROBLEM TO BE SOLVED: To provide a synthesis method of 1,3-dioxolane or 2-hydroxycarboxylic acid ester having improved, moderate and technically performable temperature-sensitive and/or acid-sensitive functional groups.SOLUTION: 1,3-dioxolane-2-one represented by the general formula (3) is prepared by a basic catalyst and further 2-hydroxycarboxylic acid ester represented by the general formula (5) is prepared by the basic catalyst. In general formula (3) and general formula (5), Rand Rare a hydrogen atom, an aryl or a heteroaryl group and the like, Rand Rare a saturated or a monovalent or a polyvalent unsaturated carbon ring and the like, and Ris an organic group.
申请公布号 JP2014058515(A) 申请公布日期 2014.04.03
申请号 JP20130186485 申请日期 2013.09.09
申请人 BOEHRINGER INGELHEIM PHARMA GMBH & CO KG 发明人 JOERG BRANDENBURG;HANFRIED BALTES;DACH ROLF
分类号 C07D491/113;C07B61/00;C07D409/04;C07D491/18 主分类号 C07D491/113
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