发明名称 PHARMACEUTICAL COMBINATION OF A VEGFR INHIBITOR AND A MEK INHIBITOR USEFUL FOR TREATING CANCER
摘要 The present invention relates to a method of treating cancer in a human and to pharmaceutical combinations useful in such treatment. In particular, the method relates to a cancer treatment method that includes administering 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methylbenzenesulfonamide, or a pharmaceutically acceptable salt thereof, and N-{3-[3-cyclopropyl-5-(2-fluoro-4-iodo-phenylamino)6,8-dimethy; -2,4,7-trioxo-3,4,6,7-tetrahydro-2H-pyrido[4,3-d]pyrimidin-1-yl]phenyl}acetamide, or a pharmaceutically acceptable salt or solvate thereof, to a human in need thereof.
申请公布号 EP2608790(A4) 申请公布日期 2014.04.02
申请号 EP20110820572 申请日期 2011.08.24
申请人 GLAXOSMITHKLINE LLC 发明人 GILMER, TONA, M.;KUMAR, RAKESH;LIU, LI
分类号 A61K31/506;A61K9/20;A61K9/48;A61K31/519;A61P35/00 主分类号 A61K31/506
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