EBV-SPECIFIC CYTOTOXIC T-LYMPHOCYTES FOR THE TREATMENT OF LOCOREGIONAL NASOPHARYNGEAL CARCINOMA (NPC)

摘要

The present invention concerns methods and compositions for treatment of locoregional nasopharyngeal carcinoma utilizing EBV-specific T cells. In specific embodiments, locoregional solid tumors are treated with cytotoxic T lymphocytes specific for at least one EBV antigen, such as LMP2, LMP1, and/or EBNA1, for example.