摘要 |
PROBLEM TO BE SOLVED: To provide methods and compositions for reducing toxicity associated with administration of vitamin D, its 25-hydroxylated and 1-hydroxylated forms, and analogs thereof.SOLUTION: The present invention provides pharmaceuticals for use in treatment of subjects, including a vitamin Dsupplement and a vitamin Dsupplement to be co-administered to the subjects, where the vitamin Dsupplement is 25-hydroxyvitamin Dand the vitamin Dsupplement is ergocalciferol. |