发明名称 |
METHOD FOR PRODUCING LAYERED CELL SHEETS, LAYERED CELL SHEETS HAVING VASCULAR NETWORK OBTAINED THEREBY, AND METHOD FOR UTILIZING SAME |
摘要 |
<p>A method for producing multilayered cell sheets, including producing a vascular bed which includes an artery-vein loop and in which a capillary vascular network is constructed; layering cell sheets on the vascular bed; and perfusing a culture medium in vitro to construct a vascular network in the cell sheets. The production method enables vascular networks to be constructed in cell sheets and enables thick multilayered cell sheets to be easily produced by layering the cell sheets. Such thick multilayered cell sheets are useful as in vivo tissue-like products for regenerative medicine for various tissues and for evaluation of drugs and the like.</p> |
申请公布号 |
EP2617810(A4) |
申请公布日期 |
2014.03.26 |
申请号 |
EP20110825224 |
申请日期 |
2011.09.14 |
申请人 |
TOKYO WOMEN'S MEDICAL UNIVERSITY |
发明人 |
SEKINE, HIDEKAZU;SHIMIZU, TATSUYA;OKANO, TERUO |
分类号 |
C12N5/071;A61L27/00;C12N5/077;C12N5/0775 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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