| 发明名称 |
1H-QUINAZOLINE-2,4-DIONES |
| 摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to N-[2,4-dioxo-6-(tetrahydrofuran-2-yl)-7-trifluoromethyl-1,4-dihydro-2H-quinazolin-3-yl]methanesulphonamide and N-[6-(1-isopropoxyethyl)-2,4-dioxo-7-trifluoromethyl-1,4-dihydro-2H- quinazolin-3-yl] methanesulphonamide, having antagonistic activity on the AMPA receptor. The invention also relates to a pharmaceutical composition.EFFECT: use of said compounds to produce drugs for treating AMPA mediated conditions and primarily for treating epilepsy or schizophrenia.6 cl, 81 ex |
| 申请公布号 |
RU2509764(C2) |
申请公布日期 |
2014.03.20 |
| 申请号 |
RU20110131276 |
申请日期 |
2006.04.10 |
| 申请人 |
NOVARTIS AG |
发明人 |
ALL'GAJER KHANS;OBERSON IV;KARKASH DAVID;FLERSHAJM FILIPP;GIBURDENSH KRISTEL';FRESHTL' VOL'FGANG;KALLEN JERG;KOLLER MANUEHL';MATTE ANRI;NOTSULAK JOAKHIM;OREN DAVID;RENO ZHOANNE |
| 分类号 |
C07D239/96;A61K31/517;A61P25/08;A61P25/18;C07C229/56;C07C229/64;C07C229/66;C07C255/18;C07C265/12;C07D207/32;C07D207/337;C07D231/12;C07D237/08;C07D239/26;C07D241/12;C07D249/06;C07D263/32;C07D307/16;C07D307/54;C07D309/12;C07D401/04;C07D403/04;C07D405/04;C07D413/04 |
主分类号 |
C07D239/96 |
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