| 发明名称 |
Process for preparing 5-biphenyl-4-amino-2-methyl pentanoic acid |
| 摘要 |
<p>The present invention relates to pyrrolidin-2-ones according to the formula (1), or salts thereof, wherein R1 is hydrogen or a nitrogen protecting group, methods for their preparation and their use in the preparation of NEP-inhibitors, particularly in the preparation of N-(3-carboxyl-1 -oxopropyl)-(4S)-(p-phenylphenylmethyl)-4-amino-(2R) methyl butanoic acid ethyl ester or salt thereof. R1 (1)</p> |
| 申请公布号 |
AU2012203155(B2) |
申请公布日期 |
2014.03.20 |
| 申请号 |
AU20120203155 |
申请日期 |
2012.05.29 |
| 申请人 |
NOVARTIS AG |
发明人 |
BANZIGER, MARKUS;HAWKER, STEVEN;WIETFELD, BERNHARD;HOOK, DAVID;SEDELMEIER, GOTTFRIED;RUCH, THOMAS;RISS, BERNHARD;CISZEWSKI, LECH;NAPP, MATTHIAS;WAYKOLE, LILDHAR MURLIDHAR |
| 分类号 |
C07C227/16;C07C227/22;C07C227/32;C07C229/34;C07C269/06;C07C271/22;C07D207/26;C07D207/267;C07D207/27;C07D207/277;C07D207/28;C07D207/38;C07D207/44;C07D227/02;C07F7/18 |
主分类号 |
C07C227/16 |
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