| 摘要 |
PROBLEM TO BE SOLVED: To provide an isolated peptide which is a variant, a derivative or a structural equivalent of cupredoxin, capable of inhibiting development of premalignant lesions in mammalian tissues.SOLUTION: There is provided a composition comprising a variant, a derivative and a structural equivalent of cupredoxin which suppresses development of premalignant lesions in mammalian cells, tissues and animals, and also provided is a use of cupredoxin and a variant, a derivative and a structural equivalent of cupredoxin as chemopreventive agents for inhibiting development of premalignant lesions and ultimately cancers in mammals. |
