发明名称 |
1'-SUBSTITUTED-CARBA-NUCLEOSIDE PRODRUGS FOR ANTIVIRAL TREATMENT |
摘要 |
<p>Provided are prodrugs of pyrrolo[1,2-f][1,2,4]triazin-7-yl nucleoside phosphates wherein the 1′position of the nucleoside sugar is substituted with CN. The compounds, compositions, and methods provided are useful for the treatment Hepatitis C infections.</p> |
申请公布号 |
EP2576534(B1) |
申请公布日期 |
2014.03.19 |
申请号 |
EP20110725838 |
申请日期 |
2011.05.26 |
申请人 |
GILEAD SCIENCES, INC. |
发明人 |
CHO, AESOP;KIM, CHOUNG, U.;RAY, ADRIAN, S.;ZHANG, LIJUN |
分类号 |
C07D309/10;A61K31/40;A61P31/14 |
主分类号 |
C07D309/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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