发明名称 PROCESS FOR PRODUCING 1-(3,4-DICHLOROBENZYL)-5-OCTYLBIGUANIDE OR A SALT THEREOF
摘要 The present invention provides a process for producing 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof, the process comprising reacting 1-cyano-3-octylguanidine or a salt thereof, with 3,4-dichlorobenzylamine or a salt thereof, in an ester-based organic solvent. According to the present invention, the reaction can be carried out at a low temperature using general-purpose equipment, and 1-(3,4-dichlorobenzyl)-5-octylbiguanide or a salt thereof can be produced in a high yield by a safe and easy process.
申请公布号 CA2661272(C) 申请公布日期 2014.03.18
申请号 CA20072661272 申请日期 2007.08.28
申请人 OTSUKA PHARMACEUTICAL CO., LTD. 发明人 OKAICHI, YOSHIHIKO;TADA, NOBUHITO;NOMI, DAISUKE;FUJITA, NOBUHISA;TSUJI, KOICHI;YAMAGUCHI, TAIZO;MUGURUMA, YASUAKI;TSUJIMORI, HISAYUKI
分类号 C07C277/08;C07C279/26 主分类号 C07C277/08
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