发明名称 |
SUSTAINED-RELEASE SOLID PREPARATION FOR ORAL USE |
摘要 |
It is intended to avoid dose dumping of a drug and improve the dissolution properties of the drug in the lower gastrointestinal tract, and thereby provide a sustained-release pellet preparation for oral administration that reliably exhibits its main pharmacological effect when orally administered once or twice a day. The present invention provides a sustained-release preparation obtained by mixing of (A) a pharmacologically active drug, (B) hydroxypropyl methylcellulose acetate succinate, (C) a plasticizer, and (D) polyethylene glycol followed by extrusion granulation. |
申请公布号 |
US2014070446(A1) |
申请公布日期 |
2014.03.13 |
申请号 |
US201314079859 |
申请日期 |
2013.11.14 |
申请人 |
DAIICHI SANKYO COMPANY, LIMITED |
发明人 |
KANAMARU TARO;TAJIRI SHINICHIRO |
分类号 |
A61K47/38;A61K9/14;A61K31/404;A61K31/437;A61K47/14;A61K47/34 |
主分类号 |
A61K47/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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