USE OF FK506 FOR THE TREATMENT OF PULMONARY ARTERIAL HYPERTENSION
摘要
A method of reducing pulmonary arterial hypertension in a mammal that employs FK506 is provided. In certain embodiments, the method comprises administering FK506 to a mammal having pulmonary arterial hypertension associated with defective MBPR2 signaling at a dosage sufficient to reduce blood pressure in the pulmonary artery of the mammal.
申请公布号
EP2704711(A1)
申请公布日期
2014.03.12
申请号
EP20120779354
申请日期
2012.04.30
申请人
THE BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY
发明人
SPIEKERKOETTER, EDDA;RABINOVITCH, MARLENE;BEACHY, PHILIP, A.;SOLOW-CORDERO, DAVID