发明名称 |
SPIRO-OXINDOLE MDM2 ANTAGONISTS |
摘要 |
Provided herein are compounds, compositions, and methods in the field of medicinal chemistry. The compounds and compositions provided herein relate to spiro-oxindoles which function as antagonists of the interaction between p53 and MDM2, and their use as therapeutics for the treatment of cancer and other diseases. |
申请公布号 |
KR20140027913(A) |
申请公布日期 |
2014.03.07 |
申请号 |
KR20137015168 |
申请日期 |
2011.11.11 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;ASCENTA LICENSING CORPORATION;SANOFI |
发明人 |
WANG SHAOMENG;ZHAO YUJUN;SUN WEI;KUMAR SANJEEV;LEOPOLD LANCE;DEBUSSCHE LAURENT;BARRIERE CEDRIC;CARRY JEAN CHRISTOPHE;AMANING KWAME;GUO MING |
分类号 |
C07D487/10;A61K31/407;A61P35/00 |
主分类号 |
C07D487/10 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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