| 发明名称 |
TOLEROGENIC SYNTHETIC NANOCARRIERS TO REDUCE IMMUNE RESPONSES TO THERAPEUTIC PROTEINS |
| 摘要 |
Disclosed are synthetic nanocarrier methods, and related compositions, comprising administering B cell and/or MHC Class II-restricted epitopes of an antigen and immunosuppressants in order to reduce antigen-specific activation of innate immune cells. |
| 申请公布号 |
EP2701705(A2) |
申请公布日期 |
2014.03.05 |
| 申请号 |
EP20120776063 |
申请日期 |
2012.04.27 |
| 申请人 |
SELECTA BIOSCIENCES, INC. |
发明人 |
FRASER, CHRISTOPHER;KISHIMOTO, TAKASHI, KEI;MALDONADO, ROBERTO, A. |
| 分类号 |
A61K31/445;A61K9/14;A61K9/16;A61K31/00;A61K39/00;A61K39/36;A61K39/38;A61K39/395;A61K47/30;A61K47/48;A61P29/00;B82Y5/00 |
主分类号 |
A61K31/445 |
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