发明名称 |
Probiotic strain and antimicrobial peptide derivedtherefrom |
摘要 |
A strain of Enterococcus mundtii has probiotic qualities. The strain of E. mundtii (ST4SA) produces an antimicrobial peptide which exhibits antimicrobial activity against a broad range of bacteria. An isolated nucleotide sequence codes for the antimicrobial peptide (peptide ST4SA). A process is also provided for the production of a peptide which comprises cultivating Enterococcus mundtii strain ST4SA in a nutrient medium under micro-aerophilic conditions at a temperature of between 10° C. and 45° C., until a recoverable quantity of the peptide is produced, and recovering the peptide. The isolated peptide may be used as an antimicrobial agent in a liquid formulation or a gel formulation as a topical treatment and may also be used as an antimicrobial agent following encapsulation in a polymer. |
申请公布号 |
AP2841(A) |
申请公布日期 |
2014.02.28 |
申请号 |
AP20080004626 |
申请日期 |
2007.05.25 |
申请人 |
CIPLA MEDPRO RESEARCH AND DEVELOPMENT 'PTY' LTD |
发明人 |
DICKS LEON MILNER THEODORE;TODOROV SVETOSLAV DIMITROV;KNOETZE HENDRIETTE |
分类号 |
C12N1/20;A61K35/74;A61K38/16;C07K14/315;C12R1/46 |
主分类号 |
C12N1/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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