发明名称 |
METHOD AND KIT FOR THE DETECTION OF GENES ASSOCIATED WITH PIK3CA MUTATION AND INVOLVED IN PI3K/AKT PATHWAY ACTIVATION IN THE ER-POSTITIVE AND HER2-POSITIVE SUBTYPES WITH CLINICAL IMPLICATIONS |
摘要 |
A method to determine the clinical outcome of breast tumour affecting a patient if treated with an antitumoural agent against breast tumour, the said method comprising the step of assaying a sample of a breast tumour from said patient for an expression level of selected genes, by contacting mRNA sequences from the cells of this breast tumour with a set of more than 3 nucleotide sequences related to human mutated PIK3CA. |
申请公布号 |
US2014056881(A1) |
申请公布日期 |
2014.02.27 |
申请号 |
US201314032984 |
申请日期 |
2013.09.20 |
申请人 |
UNIVERSITE LIBRE DE BRUXELLES |
发明人 |
SOTIRIOU CHRISTOS;LOI SHERENE;MCARTHUR GRANT;HAIBE-KAINS BENJAMIN |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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