发明名称 |
Ophthalmic formulation of vascular endothelial growth factor antagonist, a method of producing the same and syringe suitable for intravitreal administration comprising the same |
摘要 |
Ophthalmic formulations of a vascular endothelial growth factor (VEGF)-specific fusion protein antagonist are provided suitable for intravitreal administration to the eye. The ophthalmic formulations include a stable liquid formulation and a lyophilizable formulation. Preferably, the protein antagonist has the amino acid sequence showing in SEQ ID No: 4 or amino acids 27-457 of SEQ ID No: 4. |
申请公布号 |
IL195788(A) |
申请公布日期 |
2014.02.27 |
申请号 |
IL20080195788 |
申请日期 |
2008.12.08 |
申请人 |
REGENERON PHARMACEUTICALS INC. |
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