摘要 |
FIELD: chemistry.SUBSTANCE: invention relates to a method of producing acyclovir 2/3 hydrate, which involves mixing acyclovir with water in weight ratio of 1:5-50, dissolving at 50-100°C, filtering, cooling the filtrate at 0-30° to deposit crystals, collecting crystals by filtering and drying the crystals at 0-150°C for 0.5-24 hours to obtain acyclovir 2/3 hydrate having a stable crystalline structure.EFFECT: preparation process is simple and suitable for industrial production.10 cl, 4 dwg, 1 tbl, 15 ex |