发明名称 METHOD OF PREPARING ACYCLOVIR 2/3 HYDRATE
摘要 FIELD: chemistry.SUBSTANCE: invention relates to a method of producing acyclovir 2/3 hydrate, which involves mixing acyclovir with water in weight ratio of 1:5-50, dissolving at 50-100°C, filtering, cooling the filtrate at 0-30° to deposit crystals, collecting crystals by filtering and drying the crystals at 0-150°C for 0.5-24 hours to obtain acyclovir 2/3 hydrate having a stable crystalline structure.EFFECT: preparation process is simple and suitable for industrial production.10 cl, 4 dwg, 1 tbl, 15 ex
申请公布号 RU2508291(C2) 申请公布日期 2014.02.27
申请号 RU20110143379 申请日期 2010.03.17
申请人 CHZHETSZIANG CHERIOTIR FARMAS'JUTIKAL KO., LTD. 发明人 PU TUN;FAN' I;CHEHN' TJAN';LEHJ MIN;VAN NAJSIN;JAN' CHZHEHN';JAN' TSZJAN'MIN
分类号 C07D473/18;A61K31/522;A61P31/12 主分类号 C07D473/18
代理机构 代理人
主权项
地址