SURFACE MODIFICATION METHOD OF QUANTUM DOTS AND IN VIVO OPTICAL IMAGING THEREOF

摘要

The present invention relates to a manufacturing method for quantum dots comprising: a step of manufacturing a quantum dot nanoparticle solution; a step of adding surface modification materials in the quantum dot nanoparticle solution; a step of adding water the quantum dot nanoparticle solution added with the surface modification materials and separating a water layer from a reaction solution added with the water; a step of manufacturing quantum dot nanoparticles coated with cysteamine including a process of obtaining the quantum dot nanoparticles coated with cysteamine by drying the obtained water layer after obtaining the water layer separated from the reaction solution; and a step of inducing one water-soluble monosaccharide selected from the group consisting of gluconic acid, citric acid, propionic acid, butyric acid and oleic acid.