| 发明名称 |
MONOCLONAL ANTIBODY AGAINST AMYLOID BETA PROTEIN AND USE THEREOF |
| 摘要 |
PROBLEM TO BE SOLVED: To provide a monoclonal antibody that may be used in the prevention, treatment and diagnosis of Alzheimer disease or other neurodegenerative disorder.SOLUTION: An isolated antibody binds with greater specificity to an amyloid beta (A&bgr;) protein globulomer than to an amyloid beta protein monomer. An monoclonal antibody is produced by a hybridoma having American Type Culture Collection designation number PTA-7238 or PTA-7407, and these hybridomas. |
| 申请公布号 |
JP2014037413(A) |
申请公布日期 |
2014.02.27 |
| 申请号 |
JP20130176314 |
申请日期 |
2013.08.28 |
| 申请人 |
ABBVIE INC;ABBOTT GMBH & CO KG |
发明人 |
LABKOVSKY BORIS;STEFAN BARGHORN;HILLEN HEINZ;EBERT ULRICH;STRIEBINGER ANDREAS R;KELLER PATRICK |
| 分类号 |
C07K16/18;A61K39/00;A61K39/395;A61K47/42;A61P25/28;C12N5/10;C12N15/02;C12N15/09;G01N33/15;G01N33/50;G01N33/53;G01N33/566;G01N33/577 |
主分类号 |
C07K16/18 |
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