| 摘要 |
<p>1,267,591. Antigenic compositions. NATIONAL RESEARCH DEVELOPMENT CORP. 23 Feb., 1970 [26 Feb., 1969], No. 10229/69. Heading A5B. A process for the production of a vaccine for protection against a virus of the tick-borne encephalitis group, e.g. louping-ill virus, comprises cultivating the virus in cell or tissue culture, separating the culture fluid and treating the culture fluid with a water-miscible or soluble alcohol, ketone or other protein precipitant to cause precipitation of the antigenic material and formulating the antigenic material present in the precipitate into vaccine form. The virus may be inactivated before the precipitation step, e.g. using formalin, and the antigenic material may be separated from unwanted protein before incorporation into the vaccine. The vaccine may contain an adjuvant such as a hydrocarbon oil and a bacteriostat such as phenol. The vaccines may be used for protecting cattle and sheep.</p> |
