| 发明名称 |
Immunostimulatory G, U-containing oligoribonucleotides |
| 摘要 |
Compositions and methods relating to immunostimulatory RNA oligomers are provided. The immunostimulatory RNA molecules are believed to represent natural ligands of one or more Toll-like receptors, including Toll-like receptor 7 (TLR7) and Toll-like receptor 8 (TLR8). The compositions and methods are useful for stimulating immune activation. Methods useful for screening candidate immunostimulatory compounds are also provided. |
| 申请公布号 |
US8658607(B2) |
申请公布日期 |
2014.02.25 |
| 申请号 |
US20060368333 |
申请日期 |
2006.03.03 |
| 申请人 |
LIPFORD GRAYSON B.;BAUER STEFAN;WAGNER HERMANN;ZOETIS BELGIUM |
发明人 |
LIPFORD GRAYSON B.;BAUER STEFAN;WAGNER HERMANN |
| 分类号 |
A01N43/04;G01N33/50;A61K31/205;A61K31/7088;A61K31/7105;A61K31/7115;A61K31/712;A61K31/7125;A61K38/00;A61K38/21;A61K39/00;A61K39/02;A61K39/35;A61K39/395;A61K45/00;A61K45/06;A61K47/20;A61K48/00;A61P35/00;A61P37/04;C07H;C07H21/02;C12N5/00;C12N15/09;C12P19/34;C12Q1/02;C12Q1/68;G01N33/15;G01N33/566 |
主分类号 |
A01N43/04 |
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