| 摘要 |
A compound of the formula (1): (see formula 1) or an optical isomer thereof, an oxide form thereof, or a pharmaceutically acceptable addition salt thereof, in which: R1 is -O-R'1 or -NR'1R"1, wherein R'1 and R"1 are each H or optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, or heteroaryl; R2 is: optionally substituted alkyl, alkenyl or alkynyl radical; an aryl radical, optionally substituted and/or optionally fused to a monocyclic or polycyclic, saturated or unsaturated 5- to 8-membered nucleus optionally containing one or more hetero atoms chosen from O, N and S, the said nucleus itself being optionally substituted, or a saturated, unsaturated or aromatic, optionally substituted 5- to 8-membered monocyclic heterocyclic radical; R3 is H or optionally substituted alkyl; and A is a linear or branched C1-6 alkylene chain; the processes for the preparation of these compounds, the uses thereof for the treatment of dsylipidaemia, atherosclerosis and diabetes, and the pharmaceutical compositions comprising them. |
