发明名称 |
METHOD FOR PRODUCING SHEET-LIKE PANCREATIC ISLET |
摘要 |
<p>The present invention provides a method of producing a sheet-like pancreatic islet, comprising culturing an isolated pancreatic islet in a culture vessel, wherein a polypeptide comprising an EC1 domain of E-cadherin and having a binding ability to said E-cadherin is fixed on or applied to a surface of a solid phase, while being adhered to the solid phase surface for a period sufficient for the pancreatic islet to take a sheet-like form.</p> |
申请公布号 |
EP2695935(A1) |
申请公布日期 |
2014.02.12 |
申请号 |
EP20120767379 |
申请日期 |
2012.04.06 |
申请人 |
OTSUKA PHARMACEUTICAL FACTORY, INC. |
发明人 |
AZUMA, KOJI;FUJITA, YASUTAKA;YAGUCHI, HIROSHI;HARADA, MIWA |
分类号 |
C12N5/071;A61K47/48;C07K14/47;C07K14/705;C07K16/28;C07K17/14 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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