发明名称 |
PHARMACEUTICAL COMPOSITION OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF FOR THE PREVENTION OR TREATMENT OF CIRCADIAN CLOCK RELATED DISEASES CONTAINING 2-ETHOXYPROPIONIC ACID DERIVATIVE AS AN ACTIVE INGREDIENT |
摘要 |
The present invention relates to a pharmaceutical composition for the prevention or treatment of circadian clock related diseases containing a 2-ethoxypropionic acid derivative or pharmaceutically acceptable salt thereof as an active ingredient. The 2-ethoxypropionic acid derivative controls a function of CRY1/2 and promotes the activity of CLOCK:BMAL1 dimer for effectively controlling circadian clock molecule network damaged by genetic or environmental causes, and the composition containing the 2-ethoxypropionic acid derivative or pharmaceutically acceptable salt thereof as an active ingredient can be usefully applied to the prevention or treatment of circadian clock related diseases including sleep disorder, metabolic disorder, mood disorder, and cancer. [Reference numerals] (AA) Example 4; (BB,DD) Input; (CC,EE) Developing solvent; (FF) Bait + Example 4 |
申请公布号 |
KR20140017332(A) |
申请公布日期 |
2014.02.11 |
申请号 |
KR20120084181 |
申请日期 |
2012.07.31 |
申请人 |
SNU R&DB FOUNDATION |
发明人 |
SUH, YOUNG GER;KIM, KYUNG JIN;JUNG, JONG WHA;KIM, NAM JUNG;YUN, HWA YOUNG;JANG, JAE BONG;SON, GI HOON;CHUNG, SOO YOUNG;CHUN, SUNG KOOK;LEE, JI YEON;CHUNG, YOUN TAEK |
分类号 |
A61K31/192;A61K31/185;A61P25/20;C07C309/66 |
主分类号 |
A61K31/192 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|