发明名称 USE OF HISTONE DEACETYLASE INHIBITORS FOR THE CARE OF PHILADELPHIA-NEGATIVE MYELOPROLIFERATIVE SYNDROMES
摘要 The use of substances capable of inhibiting one or more enzymes of the histone deacetylase family (histone deacetylase inhibitors) for the therapeutic treatment of Philadelphia-negative myeloproliferative syndromes (polycythemia vera, essential thrombocythemia or idiopathic myelofibrosis) is described. The dosage of the above-mentioned substances is significantly lower than that normally used for the care of other tumour syndromes and may be from 10 to 150 mg/day/patient.
申请公布号 US2014039059(A1) 申请公布日期 2014.02.06
申请号 US201314047391 申请日期 2013.10.07
申请人 ITALFARMACO SPA 发明人 OLDONI TIZIANO;MASCAGNI PAOLO;RAMBALDI ALESSANDRO;BARBUI TIZIANO
分类号 A61K31/167;A61K45/06 主分类号 A61K31/167
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