发明名称 |
USE OF EPIGALLOCATECHIN GALLATE AS AN ANTIVIRAL AGENT AGAINST INFECTIONS BY THE HEPATITIS C VIRUS |
摘要 |
<p>The present invention relates to a flavonoid compound having the formula I, where R3, R5 and/or R7 is a group having the formula II, or R1 and R2 are both OH groups, or to one of the pharmaceutically acceptable salts or esters thereof, for use as an antiviral agent in the treatment and/or prevention of a hepatitis C virus (HCV) infection. The invention also relates to an ex vivo method for reducing the infectivity of HCV or for inactivating HCV, including a step of contacting said hepatitis C virus with a compound having the formula (I).</p> |
申请公布号 |
EP2691091(A1) |
申请公布日期 |
2014.02.05 |
申请号 |
EP20120711160 |
申请日期 |
2012.03.28 |
申请人 |
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);INSTITUT PASTEUR DE LILLE |
发明人 |
SERON, KARIN;DUBUISSON, JEAN;ROUILLE, YVES;WYCHOWSKI, CZESLAW |
分类号 |
A61K31/353;A61P31/14 |
主分类号 |
A61K31/353 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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