发明名称 |
USE OF BLOOD OR TISSUE BACTERIOME FOR PREDICTION, DIAGNOSIS AND PREVENTION OF METABOLIC DISEASES AND THEIR CARDIOVASCULAR COMPLICATIONS |
摘要 |
The present invention relates to the use of the bacterial flora for vaccine development, identification of therapeutic targets and prediction and/or diagnosis of metabolic diseases, such as diabetes, overweight and obesity, and their cardiovascular complications. In particular, the present invention provides immunogenic or vaccinal composition for preventing metabolic diseases and cardiovascular complications using attenuated or inactivated bacterial flora, or antigens derived thereof. The present invention also provides methods for identifying prognostic markers for metabolic diseases onset and cardiovascular complications and methods for in vitro prognosis of metabolic diseases and cardiovascular complications using bacterial flora. |
申请公布号 |
EP2691111(A1) |
申请公布日期 |
2014.02.05 |
申请号 |
EP20120712273 |
申请日期 |
2012.04.02 |
申请人 |
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM);CHU DE TOULOUSE |
发明人 |
BURCELIN, RÉMY;AMAR, JACQUES;GARIDOU, LUCILE;CHABO, CHANTAL |
分类号 |
A61K39/02;C12Q1/68;G01N33/68 |
主分类号 |
A61K39/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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