发明名称 |
Method for screening of patient to be administered with pharmaceutical agent comprising anti-cancer antibody as active ingredient |
摘要 |
The present invention provides a method for screening a patient to be administered with a pharmaceutical composition which comprises an anti-cancer antibody as an active ingredient, said method comprising collecting samples from patients who expresses an antigen which is recognized by the anti-cancer antibody, measuring cadherin function in the samples, and selecting a patient whose the cadherin function is decreased or deleted; a method for screening a patient who has a high efficacy ratio for a pharmaceutical composition which comprises an anti-cancer antibody as an active ingredient; and a method for improving an efficacy ratio for a pharmaceutical composition which comprises an anti-cancer antibody as an active ingredient. |
申请公布号 |
US8642032(B2) |
申请公布日期 |
2014.02.04 |
申请号 |
US20080666716 |
申请日期 |
2008.06.26 |
申请人 |
SATO TAKASHI;KIMOTO NAOYA;OHKI YUJI;FURUYA AKIKO;ISHIDA HIROYUKI;OCHIAI ATSUSHI;KYOWA HAKKO KIRIN CO., LTD.;JAPAN AS REPRESENTED BY PRESIDENT OF NATIONAL CANCER CENTER |
发明人 |
SATO TAKASHI;KIMOTO NAOYA;OHKI YUJI;FURUYA AKIKO;ISHIDA HIROYUKI;OCHIAI ATSUSHI |
分类号 |
A61K39/395;C12Q1/68;G01N33/574 |
主分类号 |
A61K39/395 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|