发明名称 Method for screening of patient to be administered with pharmaceutical agent comprising anti-cancer antibody as active ingredient
摘要 The present invention provides a method for screening a patient to be administered with a pharmaceutical composition which comprises an anti-cancer antibody as an active ingredient, said method comprising collecting samples from patients who expresses an antigen which is recognized by the anti-cancer antibody, measuring cadherin function in the samples, and selecting a patient whose the cadherin function is decreased or deleted; a method for screening a patient who has a high efficacy ratio for a pharmaceutical composition which comprises an anti-cancer antibody as an active ingredient; and a method for improving an efficacy ratio for a pharmaceutical composition which comprises an anti-cancer antibody as an active ingredient.
申请公布号 US8642032(B2) 申请公布日期 2014.02.04
申请号 US20080666716 申请日期 2008.06.26
申请人 SATO TAKASHI;KIMOTO NAOYA;OHKI YUJI;FURUYA AKIKO;ISHIDA HIROYUKI;OCHIAI ATSUSHI;KYOWA HAKKO KIRIN CO., LTD.;JAPAN AS REPRESENTED BY PRESIDENT OF NATIONAL CANCER CENTER 发明人 SATO TAKASHI;KIMOTO NAOYA;OHKI YUJI;FURUYA AKIKO;ISHIDA HIROYUKI;OCHIAI ATSUSHI
分类号 A61K39/395;C12Q1/68;G01N33/574 主分类号 A61K39/395
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