| 摘要 |
The inventions provides a method of treating a human subject for C. difficile infection comprising administering orally a therapeutically effective dose of an antibiotic (for example 50 mg to 750 mg) which is selective for C. difficile over Gram-negative bacteria which are 5 components of natural healthy gut flora, wherein the average systemic plasma level of the antibiotic and any metabolites thereof does not exceed 5 ng/mL, for example is 4, 3, or 2 ng/mL or less. |
