| 发明名称 |
CYCLOALKANOPYROLOCARBAZOLE DERIVATIVES AND THE USE THEREOF AS PARP, VEGFR2 AND MLK3 INHIBITORS |
| 摘要 |
The present invention is directed to novel multicyclic molecules that mediate enzymatic activity. In particular, the compounds may be effective in the treatment of diseases or disease states related to the activity of PARP, VEGFR2, and MLK3 enzymes, including, for example, neurodegenerative diseases, inflammation, ischemia, and cancer. |
| 申请公布号 |
HK1131747(A1) |
申请公布日期 |
2014.01.30 |
| 申请号 |
HK20090109830 |
申请日期 |
2009.10.23 |
| 申请人 |
CEPHALON INC. |
发明人 |
CHATTERJEE, SANKAR;DIEBOLD, JAMES, L.;DUNN, DEREK;HUDKINS, ROBERT, L.;DANDU, REDDEPPAREDDY;WELLS, GREGORY, J.;ZULLI, ALLISON, L. |
| 分类号 |
A61K;A61K31/407;A61K31/41;A61K31/4178;A61K31/4196;A61K31/427;A61K31/4412;A61K31/4439;A61K31/4453;A61K31/497;A61K31/501;A61K31/5377;A61P;A61P3/10;A61P9/10;A61P15/00;A61P17/06;A61P25/14;A61P25/16;A61P25/28;A61P27/02;A61P29/00;A61P35/00;A61P43/00;C07D471/14;C07D487/04;C07D491/04;C07D491/14;C07D495/04;C07D519/00 |
主分类号 |
A61K |
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