| 发明名称 |
PIPERIDINYL DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY |
| 摘要 |
The present invention relates to compounds of formula Ib and Ib' or pharmaceutically acceptable salts thereof which are modulators of MIP-1 or CCR-1. There are also disclosed compositions based on said compounds and methods of treating and preventing inflammatory diseases such as asthma and allergic diseases, as well as autoimmune pathologies such as rheumatoid arthritis and transplant rejection using said modulators. |
| 申请公布号 |
EA019192(B1) |
申请公布日期 |
2014.01.30 |
| 申请号 |
EA20080001757 |
申请日期 |
2007.01.25 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY |
发明人 |
CARTER PERCY, H.;CAVALLARO CULLEN, L.;DUNCIA JOHN, V.;GARDNER DANIEL, S.;HYNES JOHN;LIU RUI-QIN;SANTELLA JOSEPH, B.;DODD DHARMPAL, S. |
| 分类号 |
C07D211/52;A61K31/445;A61K31/4523;A61K31/454;A61P19/02;A61P37/00;C07D211/18;C07D211/38;C07D211/58;C07D211/70;C07D401/12;C07D401/14;C07D405/12;C07D409/12;C07D413/12;C07D417/12;C07D417/14;C07D471/04;C07D487/04;C07D491/10;C07D491/107 |
主分类号 |
C07D211/52 |
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