Therapeutic Anti-Virus VLPS

摘要

This invention provides therapeutic viruses (TV) and methods to inhibit the propagation of a target virus. TVs can be rendered noninfectious by inactivating mutations, but also include sequences providing miRNA to inactivate essential mRNAs of the target virus. Methods can include provision of the TV and contact with a host cell harboring the target virus. The target virus providing the essential enzymes necessary to the replication of the TV and the TV disabling the target virus with the miRNA.