AMINOPYRAZINE DERIVATIVE AND MEDICINE

摘要

A compound represented by general formula [1] satisfying the following (I) or (II), or a pharmaceutical acceptable salt of the compound.
(I) X is CH or N; R 1 is a halogen atom,; and R 2 is H, a halogen atom, CN, [2], [3], [8], [9], an -O-alkyl, an -0-(saturated ring), etc.
[2]: -C(R C )(R D )(R E ) {R C to R E each are H, an alkyl, etc.}
[3]: -N(R F )(R G ) {R F and R G each are H, OH, amino, a (hetero) aryl, etc.}
[8]: -C(=O)R L {R L is an alkyl, OH, an alkoxy, amino, etc.}
[9]: a (substituted)phenyl;
(II) X is >C-C(=0)R B {R B is a (substituted)amino, an alkoxy, OH, etc.};
R 1 is a halogen atom; R 2 is H; R 3 is H or OH; and R 3 and R 4 each are H or an alkyl.