| 摘要 |
PURPOSE: Lactobacillus johnsonii HY7042 is provided to suppress the proliferation of Gardnerella vaginalis by producing hydrogen peroxide(H2O2), to ensure acid resistance and adhesion to vagina cells, and to treat vaginitis. CONSTITUTION: Lactobacillus johnsonii HY7042(deposit number: KCTC12033BP) suppresses the proliferation of pathogenic bacteria causing vaginitis. The strain ensures acid resistance and adhesion to epithelial cells. The proliferation of the pathogenic bacteria is suppressed by suppressing the inflammation of vagina cells after oral administration. The strain has an excellent hydrogen peroxide generation property. The pathogenic bacteria are Gardnerella vaginalis. A pharmaceutical composition for preventing and treating vaginitis contains the strain as an active ingredient. Fermented milk contains the strain as the active ingredient. A functional beverage contains the strain as the active ingredient. Health functional food contains the strain as the active ingredient. [Reference numerals] (AA) Number of pathogenic bacteria(g); (BB) Normal; (CC) Pathogenic bacteria administration; (DD) Pathogenic bacteria administration + HY7042 oral administration; (EE) Pathogenic bacteria administration + HY7042 direct administration |
