CANCER STEM CELL AND THE METHOD OF PREPARING THE SAME

摘要

The present invention relates to genetically modified neural stem cells having cancer stem cell properties, a method for preparing the neural stem cells, and a method for screening anticancer drug candidates using the neural stem cells. According to the present invention, the cancer stem cells having both cancer cell properties and stem cell properties can be easily prepared using a method for introducing y-myc gene and constitutively active form H-Ras gene into the neural stem cells in expressible form. The neural stem cells having cancer stem cell properties in the present invention is very useful for studying the process of cancer genesis and screening the anticancer drug candidates.