发明名称 |
METHODS AND COMPOSITIONS FOR THE TREATMENT OF BCR-ABL POSITIVE LYMPHOBLASTIC LEUKEMIAS |
摘要 |
In one aspect, the invention relates to compositions comprising BCR-ABL tyrosine kinase inhibitors and artemisinin analogues, derivatives thereof, or related compounds, which are useful as in treating Philadelphia chromosome positive leukemias; pharmaceutical compositions comprising the compounds; and methods of treating disorders of uncontrolled cellular proliferation associated with BCR-ABL dysfunction using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention. |
申请公布号 |
WO2013177420(A3) |
申请公布日期 |
2014.01.16 |
申请号 |
WO2013US42459 |
申请日期 |
2013.05.23 |
申请人 |
ST. JUDE CHILDREN'S RESEARCH HOSPITAL |
发明人 |
SINGH, HARPREET;WILLIAMS, RICHARD, T.;GUY, KIPLIN, R. |
分类号 |
A61K31/357 |
主分类号 |
A61K31/357 |
代理机构 |
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代理人 |
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地址 |
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