| 发明名称 |
PIPERAZINE DERIVATIVES AS ANTIMALARIAL AGENTS |
| 摘要 |
The invention relates to novel piperazine derivatives of formula I and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including pharmaceutical compositions containing one or more of those compounds and their use as medicaments for the treatment or prevention of protozoal infections, especially malaria. wherein X represents -(CH2)o-2 - or -C(=O)-; n represents the integer 0, 1 or 2; R1-R4 as described in claim 1 |
| 申请公布号 |
CA2623213(C) |
申请公布日期 |
2014.01.14 |
| 申请号 |
CA20062623213 |
申请日期 |
2006.10.20 |
| 申请人 |
ACTELION PHARMACEUTICALS LTD |
发明人 |
BINKERT, CHRISTOPH;BOSS, CHRISTOPH;CORMINBOEUF, OLIVIER;GRISOSTOMI, CORINNA;MEYER, SOLANGE |
| 分类号 |
C07D295/18;C07D209/04;C07D209/16;C07D213/26;C07D213/38;C07D213/40;C07D213/60;C07D213/74;C07D217/04;C07D217/14;C07D233/54;C07D239/42;C07D277/28;C07D307/14;C07D317/58 |
主分类号 |
C07D295/18 |
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