发明名称 |
Nucleic acid molecules conferring enhanced ethanol tolerance and microorganisms having enhanced tolerance to ethanol |
摘要 |
The present invention provides isolated nucleic acid molecules which encode a mutant acetaldehyde-CoA/alcohol dehydrogenase or mutant alcohol dehydrogenase and confer enhanced tolerance to ethanol. The invention also provides related expression vectors, genetically engineered microorganisms having enhanced tolerance to ethanol, as well as methods of making and using such genetically modified microorganisms for production of biofuels based on fermentation of biomass materials. |
申请公布号 |
US8629255(B2) |
申请公布日期 |
2014.01.14 |
申请号 |
US201113112641 |
申请日期 |
2011.05.20 |
申请人 |
BROWN STEVEN;GUSS ADAM;YANG SHIHUI;KARPINETS TATIANA;LYND LEE;SHAO XIONGJUN;UT-BATTELLE, LLC |
发明人 |
BROWN STEVEN;GUSS ADAM;YANG SHIHUI;KARPINETS TATIANA;LYND LEE;SHAO XIONGJUN |
分类号 |
C07H21/00;C12N1/00;C12N1/15;C12N15/75;C12P7/02 |
主分类号 |
C07H21/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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