发明名称 |
ENDOTHELIAL CELLS ACTIVATION BIOMARKERS CHARACTERIZING ANTIBODY MEDIATED REJECTION AND USES THEREOF |
摘要 |
Described herein are methods and kits for the detection of endothelial cell injury and/or activation and to the diagnostic of transplant antibody mediated rejection (ABMR). The invention further relates to methods and kits for diagnosing endothelial to mesenchymal transition (EndMT). In various embodiments, the methods comprise assessing expression of one, two or three biomarkers selected from Fascinl, Vimentin and Hsp47. |
申请公布号 |
WO2013150375(A3) |
申请公布日期 |
2014.01.09 |
申请号 |
WO2013IB00867 |
申请日期 |
2013.04.04 |
申请人 |
ASSISTANCE PUBLIQUE HOPITAUX DE PARIS |
发明人 |
XU-DUBOIS, YI-CHUN;RONDEAU, ERIC;PELTIER, JULIE;HERTIG, ALEXANDRE;BROCHERIOU, ISABELLE |
分类号 |
C12Q1/48;G01N33/68 |
主分类号 |
C12Q1/48 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|