发明名称 S-(CARBOXYMETHYL)-CYSTEINE PHARMACEUTICAL COMPOUND AND PREPARATION METHOD AND USE THEREOF
摘要 <p>Disclosed are S-(carboxymethyl)-cysteine compound (I) and the preparation method and the use thereof. Also disclosed are S-(carboxymethyl)-D-cysteine ammonium salt monohydrate and the use thereof in the preparation of medicines for preventing and treating diseases of the respiratory system, such as chronic obstructive pulmonary disease etc., in particular the use in preparing apophlegmatisms. The compounds can reduce the airway resistance and the production of oxide in rat COPD models, increase the level of antioxidant, and alleviate the damage caused by oxide and inflammation media to lungs.</p>
申请公布号 WO2014005543(A1) 申请公布日期 2014.01.09
申请号 WO2013CN78856 申请日期 2013.07.05
申请人 GUANGZHOU BAIYUNSHAN PHARMACEUTICAL CO., LTD. GUANGZHOU BAIYUNSHAN PHARMACEUTICAL FACTORY;GUANGZHOU INSTITUTE OF RESPIRATORY DISEASE 发明人 CHEN, MAO;ZHU, SHAOXUAN;WAN, PING;WANG, WEI;LIAO, WEI;HU, HAIRONG;FU, XIANGLIN;FENG, JIN;HUANG, BINGE;ZHANG, LIN;ZHONG, NANSHAN;ZHENG, JINPING;MO, HONGYING
分类号 C07C323/58;A61K31/198;A61P11/00;A61P11/10;C07C319/14;C07C319/28 主分类号 C07C323/58
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