发明名称 |
LIPOSOMES ACTIVE IN-VIVO ON NEURODEGENERATIVE DISEASES |
摘要 |
New liposomes are described, comprising: (i) phosphatidic acid and/or cardiolipin; (ii) apolipoprotein E (ApoE) or derivatives thereof. The so modified liposomes, administered systemically, obtain a dramatic in-vivo reduction of the amyloid plaque in the central nervous system, allowing an effective treatment of neurodegenerative diseases, in particular Alzheimer's disease. |
申请公布号 |
US2014004172(A1) |
申请公布日期 |
2014.01.02 |
申请号 |
US201213536851 |
申请日期 |
2012.06.28 |
申请人 |
MASSERINI MASSIMO;RE FRANCESCA;SANCINI GIULIO;FORLONI GIANLUIGI;SALMONA MARIO |
发明人 |
MASSERINI MASSIMO;RE FRANCESCA;SANCINI GIULIO;FORLONI GIANLUIGI;SALMONA MARIO |
分类号 |
A61K9/127;A61K38/17;A61P25/00;A61P25/28 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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