发明名称 |
PYRIDO[3,4-B]PYRAZINE DERIVATIVES AS SYK INHIBITORS |
摘要 |
A compound of formula (I): or a salt thereof; which is an inhibitor of spleen tyrosine kinase (Syk) and therefore potentially of use in treating diseases resulting from inappropriate activation of mast cells, macrophages, and B-cells and related inflammatory responses and tissue damage, for instance inflammatory disease and/or allergic disorders, and in cancer therapy, specifically heme malignancies, and autoimmune conditions. |
申请公布号 |
US2014005188(A1) |
申请公布日期 |
2014.01.02 |
申请号 |
US201214004375 |
申请日期 |
2012.03.08 |
申请人 |
ATKINSON FRANCIS LOUIS;ATKINSON STEPHEN JOHN;BARKER MICHAEL DAVID;DOUAULT CLEMENT;GARTON NEIL STUART;LIDDLE JOHN;PATEL VIPULKUMAR KANTIBHAI;PRESTON ALEXANDER G.;SHIPLEY TRACY JANE;WILSON DAVID MATTHEW;WATSON ROBERT J.;GLAXO GROUP LIMITED |
发明人 |
ATKINSON FRANCIS LOUIS;ATKINSON STEPHEN JOHN;BARKER MICHAEL DAVID;DOUAULT CLEMENT;GARTON NEIL STUART;LIDDLE JOHN;PATEL VIPULKUMAR KANTIBHAI;PRESTON ALEXANDER G.;SHIPLEY TRACY JANE;WILSON DAVID MATTHEW;WATSON ROBERT J. |
分类号 |
C07D471/04;C07D487/04 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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