发明名称 |
COMBINATION OF KANASE INHIBITORS AND USES THEREOF |
摘要 |
The present invention provides for a method for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. In another aspect, the invention provides for a method for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. In yet another aspect, a method of inhibiting phosphorylation of both Akt (S473) and Akt (T308) in a cell is set forth. The present invention also provides a pharmaceutical kit effective for treating a disease condition associated with PI3-kinase α and/or mTOR in a subject. |
申请公布号 |
EP2678018(A1) |
申请公布日期 |
2014.01.01 |
申请号 |
EP20120776536 |
申请日期 |
2012.02.23 |
申请人 |
INTELLIKINE, LLC |
发明人 |
REN, PINGDA;LIU, YI;JESSEN, KATAYOUN;GUO, XIN;ROMMEL, CHRISTIAN;WILSON, TROY, EDWARD |
分类号 |
A61K31/535;A61K31/4439;A61K31/4709;A61K31/4745;A61K31/498;A61K31/501;A61K31/517;A61K31/519;A61K31/527;A61K31/53;A61K31/5377;A61K31/541;A61K31/551;A61K45/06;A61P13/12;A61P29/00;A61P35/00;A61P37/00 |
主分类号 |
A61K31/535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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