发明名称 |
PRODUCTION OF PROTEINS AND POLYPEPTIDES |
摘要 |
A method of producing a desired non-spidroin protein or polypeptide is comprising the steps of expressing in a suitable host a fusion protein, obtaining a mixture containing the fusion protein, and optionally isolating the fusion protein. The fusion protein is comprising at least one solubility-enhancing moiety which is derived from the N-terminal (NT) fragment of a spider silk protein. It is further comprising at least one moiety which is a desired non-spidroin protein or polypeptide. Each solubility-enhancing moiety is linked directly or indirectly to the desired protein or polypeptide moiety. |
申请公布号 |
EP2547771(A4) |
申请公布日期 |
2014.01.01 |
申请号 |
EP20100848078 |
申请日期 |
2010.10.27 |
申请人 |
SPIBER TECHNOLOGIES AB |
发明人 |
JOHANSSON, JAN;RISING, ANNA;HEDHAMMAR, MY;NORDLING, KERSTIN |
分类号 |
C07K14/435;C12N15/62 |
主分类号 |
C07K14/435 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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