| 发明名称 |
NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH |
| 摘要 |
Therapeutic ureido-sulfonamide compositions having compounds with the formula R-Q-Ar-SO2NH2 are disclosed, which compounds selectively inhibit CAIX and CAXII, and which are effective to inhibit hypoxic tumor growth, suppress metastases, and impair and deplete cancer stem cells in mammals. |
| 申请公布号 |
EP2590938(A4) |
申请公布日期 |
2014.01.01 |
| 申请号 |
EP20110817596 |
申请日期 |
2011.06.22 |
| 申请人 |
METASIGNAL THERAPEUTICS INC. |
发明人 |
SUPURAN, CLAUDIU;DEDHAR, SHOUKAT;MCDONALD, PAUL, C.;CARTA, FABRIZIO |
| 分类号 |
C07C311/47;A61K31/18;A61K31/63;A61P35/00 |
主分类号 |
C07C311/47 |
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