NUCLEAR PENETRATING H4 TAIL PEPTIDES FOR THE TREATMENT OF DISEASES MEDIATED BY IMPAIRED OR LOSS OF P53 FUNCTION

摘要

Methods for using chimeric polypeptides and other compositions comprising H4 tail peptides to increase p53 activity in cells and treat diseases mediated by lack of or dysfunctional p53 function as described. Also provided are chimeric polypeptides and other compositions comprising H4 tail peptides.