发明名称 |
Processo de obtenção dos enantiômeros da cetamina e seus sais farmaceuticamente aceitáveis |
摘要 |
The present invention describes a new process for obtainment of the cetamine enantiomers, from the racemic cetamine resolutions with the aid of an agent of chiral resolution, which provides the selective crystallization of its enantiomers. The resolution agent is employed in special concentration conditions, which provides stability, reproducibility and high enantiomeric purity to the precipitated diasteromer salt, making feasible the industrial production of the S-cetamine and its pharmaceutically acceptable salts. |
申请公布号 |
BR0002693(B1) |
申请公布日期 |
2013.12.24 |
申请号 |
BR20000002693 |
申请日期 |
2000.06.19 |
申请人 |
CRISTALIA PRODUTOS QUIMICOS FARMACEUTICOS LTDA. |
发明人 |
VALTER FREIRE TORRES RUSSO;ELISA MANNOCHIO DE SOUZA RUSSO |
分类号 |
A61K31/122;A61P23/00;A61P25/04;A61P29/00;C07B57/00;C07C221/00;C07C225/12 |
主分类号 |
A61K31/122 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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